Family name Ramirez Riofrio (Ramirez Riofrio 
) , globally, is a rare surname. The cognomen Ramirez Riofrio is habitual in Latin America and the Caribbean, particularly Ecuador, where it is a rare surname, and Chile, where it is an extremely rare surname.
| VARIANT | COUNTRY |
|---|---|
| Ramirez Riofrio | Chile, Ecuador |